

£88.55 Inc VAT
Zycortal Suspension for Dogs 25mg/ml
PRESCRIPTION NEEDED (POM-V)
Zycortal (desoxycortone pivalate) is a prolonged-release injection used as replacement therapy for mineralocorticoid deficiency in dogs with primary hypoadrenocorticism (Addison’s disease). Given only by subcutaneous injection, by your vet or under close veterinary direction — this is not an oral home medicine. Most dogs also need a separate glucocorticoid prescribed alongside it.
Ordering This Prescription Medicine
A valid veterinary prescription is required before dispatch.
- Add the medicine, strength and quantity shown on your prescription to your basket.
- Upload your prescription at checkout, or send it to us afterwards by email.
- Complete checkout — we’ll verify your prescription before dispatch.
In stock
PRESCRIPTION NEEDED (POM-V)
What Zycortal is used for
Zycortal is licensed as replacement therapy for mineralocorticoid deficiency in dogs with primary hypoadrenocorticism (Addison’s disease). It replaces mineralocorticoid hormones only — most dogs also need a separate glucocorticoid (such as prednisolone) prescribed alongside it.
Strength and pack
25mg/ml desoxycortone pivalate, supplied as one 4ml vial.
How it’s given
Given by subcutaneous injection only. The starting dose is 2.2mg/kg, then individually adjusted using follow-up blood sodium/potassium checks at day 10 and day 25. The interval between doses varies by dog — commonly every 20–46 days, sometimes longer — and is set by your vet, not on a fixed schedule.
Safety information
- Not for use in dogs hypersensitive to desoxycortone pivalate
- A dog in an Addisonian crisis (severe dehydration/collapse) needs IV fluid stabilisation before starting Zycortal
- Extra caution is needed in dogs with heart disease, severe kidney or liver disease, or fluid retention
- Common effects include increased thirst and urination, tiredness, reduced appetite, vomiting, diarrhoea or shaking — contact your vet if you notice anything unusual
- Avoid skin or eye contact when handling; this product should not be given by anyone who is pregnant or breastfeeding; seek medical advice immediately if accidentally self-injected
Full prescribing information is in the product datasheet. Manufactured by Dechra.






